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  The haemorheological effects of felodipine extended release (ER), a new dihydropyridine calcium antagonist, were compared withhydrochlorothiazide (HCTZ) in 28 mild to moderate hypertensives (18 men and 10 women, aged 30-70 years) in a randomized, double-blind,crossover trial. Antihypertensive...
Type: Abstracts
  This study was designed to examine changes of hemorheological parameters and red cell aggregation particularly in essential arterial hypertensionsubjects receiving antihypertensive diuretic therapy. Fifty six female subjects were enrolled in this study. Thirty seven subjects (group I) were...
Type: Abstracts
  Eight volunteers received lignocaine 75 mg i.m. Peak plasma lignocaine concentrations (mean 0.80 microgram ml-1; range 0.31-1.86 micrograms ml-1) were attained at 30 min. Haematocrit and red cell deformability remained unchanged. Lignocaine caused small but significant decreases in plasma...
Type: Abstracts
  In addition to their effects on blood pressure, antihypertensive agents may produce additional effects on blood rheology and arterial complianceabnormalities which may play a role in target-organ damage. However, these effects may depend only on the specific pharmacological properties of certain...
Type: Abstracts
  In spite of the recent flurry of interest in n-3 fatty acids, haemorheological effects have been somewhat neglected. When quantifying blood rheology bymeans of blood viscosity, plasma viscosity, haematocrit, red cell deformability and red cell aggregation measurements, it is observed that all...
Type: Abstracts
  BACKGROUND: Calcineurin inhibitors, mainly cyclosporin A (CsA), are associated with endothelial dysfunction in renal transplant recipients (RTRs).Hemorheological disturbances including decreased erythrocyte deformability (ED), increased plasma viscosity and erythrocyte aggregation (EA) have also...
Type: Abstracts
  The usefulness of Clopidogrel as inhibitor of platelet aggregation has been demonstrated, but its effect on hemoreological parameters, such as whole blood viscosity at low and high shear rate, red cell aggregation and deformability indexes, filterability rate and and deformability of red blood...
Type: Abstracts
  Furosemide is a diuretic agent which is often given in high concentration intravenously. Since erythrocytes have a furosemide-sensitive transport system and oral application of furosemide was found to induce an echinocytic shape transformation in horses, we have analysed the influence...
Type: Abstracts
  We have evaluated blood viscosity parameters in 20 men suffering from coronary heart disease (CHD) and in 15 control subjects. Whole bloodviscosity at a standardized haematocrit of 45% was significantly increased in the CHD-patients, both at low (p less than 0.001) and high (p less than0.05)...
Type: Abstracts
  Changes in hemorheological parameters were studied in dogs following unilateral renal artery clamping (45-minute ischemia then reperfusion), with and without preoperative administration of allopurinol. Sham-operated animals were also evaluated. Blood samples were collected preoperatively, at...
Type: Abstracts

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