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Blood and plasma viscosity was measured in 13 patients with hypothyroidism before and during replacement therapy with l-thyroxine. Blood viscositywas measured at natural hematocrit and after adjustment to 40%. The values were compared to those of 12 healthy subjects. Both blood viscosity...
Tags: Levothyroxine, Whole blood viscosity (WBV), Plasma viscosity (PV), Shear rate, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Erythrocyte sedimentation rate (ESR)
Activation of N-Methyl D-Aspartate (NMDA) Receptors Has No Influence on Rheological Properties of Erythrocytes.
PURPOSE: Red blood cells (RBCs) express N-methyl D-aspartate (NMDA) receptors on their surface. We tested if NMDA receptor activation or inhibition had an influence on RBC deformability and aggregability. METHODS: Heparinized blood was drawn from healthy volunteers and centrifuged. RBCs were...
Tags: Memantine, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Erythrocyte aggregation (RBC aggregation), Erythrocyte sedimentation rate (ESR)
Failure of Pentoxifylline or Cilostazol to Improve Blood and Plasma Viscosity, Fibrinogen, and Erythrocyte Deformability in Claudication.
Peripheral artery disease is associated with altered blood rheologic properties, including increased viscosity and decreased red blood cell (RBC)deformability. Pentoxifylline and cilostazol are available therapies for intermittent claudication. Improvement of blood viscosity and erythrocyte...
Tags: Cilostazol, Pentoxifylline, Whole blood viscosity (WBV), Lipids, Erythrocyte deformability, Fibrinogen, Erythrocyte sedimentation rate (ESR), Plasma viscosity (PV)
The effects of furosemide and pentoxifylline on blood flow properties in horses were investigated. Hematologic and rheologic changes were examined in 4 horses before and 3 minutes after administration of epinephrine (1 mg, IV). The next day, hemorheologic changes were determined before and 3...
Tags: Furosemide, Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), White blood cells (WBC) (or leukocytes), Erythrocyte sedimentation rate (ESR), Hemoglobin (Hgb), Red cell filterability
Trial of Atorvastatin in Rheumatoid Arthritis (TARA): Double-Blind, Randomised Placebo-Controlled Trial.
BACKGROUND: Rheumatoid arthritis is characterised by inflammatory synovitis, articular destruction, and accelerated atherogenesis. HMG-CoA (3-hydroxy-3-methylglutarylcoenzyme A) reductase inhibitors (statins) mediate clinically significant vascular risk reduction in patients withoutinflammatory...
BACKGROUND: Diagnosis of giant cell arteritis (GCA) is based on criteria of the American College of Rheumatology. However, not all GCA patients meet these criteria and treatment may be delayed in individual patients, leading to an increased risk of complications. METHODS: In an observational...
Tags: Methylprednisolone, Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Plasma viscosity (PV)
Ileum-Targeted Steroid Therapy in Rheumatoid Arthritis: Double-Blind, Placebo-Controlled Trial of Controlled-Release Budesonide.
In order to determine whether budesonide, which is believed to exert most of its anti-inflammatory effects in the intestinal tract, has a beneficial effecton disease activity in rheumatoid arthritis (RA), we treated 26 patients with active RA in double-blind fashion with either controlled ileal-...
Tags: Budesonide, Inflammation, Hemoglobin (Hgb), Erythrocyte sedimentation rate (ESR), Plasma viscosity (PV), C-reactive protein (CRP)
Effects of echinocytosis on blood rheology and exercise performance were evaluated for 5 Thoroughbreds. Echinocytosis was induced by administration of furosemide (1 mg/kg of body weight, IM, q 12 h) for 4 days. Furosemide treatment resulted in decreases in serum sodium and serum chloride...
Tags: Furosemide, Whole blood viscosity (WBV), Plasma proteins, Erythrocyte sedimentation rate (ESR), Echinocytes
How Reliable is ESR as a Measure of Disease Activity in Rheumatoid Arthritis Treated With Hydroxychloroquine?
Forty-two patients with active rheumatoid arthritis treated with hydroxychloroquine sulphate (400 mg day-1) for six months have been compared withpatients treated with D-penicillamine (n = 14), aurothiomalate (n = 13), sulphasalazine (n = 15) and chloroquine (n = 17) to compare the changes in...
C-reactive protein (CRP) levels were measured in 105 patients with rheumatoid arthritis (RA) during treatment with slow-acting anti-rheumatoid drugsD-penicillamine, alclofenac, hydroxychloroquine, gold, sulphasalazine and azathioprine. A control group treated with aspirin alone was also included....
Tags: Hydroxychloroquine, C-reactive protein (CRP), Fibrinogen, Erythrocyte sedimentation rate (ESR)