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To determine the hemorheological effects of oral contraceptives, 50 healthy young women took no medication for 3 cycles. Subsequently they were randomized into group A and B. Group A took Diane-35, B took Microgynon each for 6 cycles. Finally 3 cycles without medication followed. Blood viscosity...
Tags: Ethinyl Estradiol and Levonorgestrel, Ethinyl Estradiol and Gestodene, Fibrinogen, Plasma viscosity (PV), Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Red cell filterability
OBJECTIVE: To determine the effect of transdermal oestrogen replacement therapy on the haemostatic balance of menopausal women. DESIGN: Open, parallel group, prospective study. SETTING: Three hospital-based menopause clinics. SUBJECTS: Fifty-two postmenopausal women receiving transdermal hormone...
Postprandial Hemorrheology and Apolipoprotein B Metabolism in Patients With Familial Hypertriglyceridemia.
Impaired postprandial lipoprotein metabolism has been found to be related to the extent of coronary artery disease. Moreover, sincedyslipoproteinemias are associated with impaired hemorrheology, we investigated the effect of postprandial hypertriglyceridemia on hemorrheologicalparameters before...
Tags: Gemfibrozil, Lipids, Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Erythrocyte aggregation (RBC aggregation), Fibrinogen
Effect of Increased Dietary Calcium on Hemorheological, Lipid and Lipid Peroxidation in Oral Contraceptive-Treated Female Rats.
Oral contraceptive (OC) steroids use has been associated with variable effects on blood lipid and rheological properties, and abnormal plasma lipidand hemorheological profiles has been shown to be in almost all conditions associated with accelerated atherosclerotic cardiovascular disorders. This...
Tags: Ethinyl Estradiol and Norgestrel, Whole blood viscosity (WBV), Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Fibrinogen, Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C)
Effects of Pravastatin Sodium and Simvastatin on Plasma Fibrinogen Level and Blood Rheology in Type II Hyperlipoproteinemia.
Elevated plasma fibrinogen level is known to progress atherosclerosis and to be one of the risk factors for the occurrence of cardiovascular diseases. The objective of this study is to evaluate the changes in plasma fibrinogen level and blood rheology in patients with type II...
Tags: Pravastatin, Simvastatin, Fibrinogen, Total cholesterol, Whole blood viscosity (WBV), Plasma viscosity (PV), Adjusted whole blood viscosity (or hematocrit-corrected blood viscosity, normalized for Hct), Shear rate, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Plasma proteins, Albumin
Effect of High-Dose Progestogen on Hemostatic Properties of Blood in Patients With Endometrial Cancer.
Fifteen cases of endometrial cancer were administered daily doses of 600 mg of MPA after surgery to prevent the recurrence of cancer. The initiation times of coagulation (time necessary for fibrin network formation) were measured with a highly sensitive damped oscillation rheometer and compared...
Tags: Medroxyprogesterone, Fibrinogen, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Platelets (or thrombocytes)
In order to investigate the effect of fenofibrate on microcirculation, 16 patients (5 female, 11 male, age 58 +/- 8 years) were studied with the aid ofnailfold capillaroscopy before and after treatment with 200 mg fenofibrate per day over six weeks. Fenofibrate resulted in a significant decrease...
Tags: Fenofibrate, Lipids, Fibrinogen, Total cholesterol, Low-density lipoprotein cholesterol (LDL-C), Apolipoprotein A-I (apo A-I), Apolipoprotein B (ApoB), Very low-density lipoprotein cholesterol (VLDL-C)
The present study aimed at testing a possible relationship between hemorrheologic factors, such as hematocrit, fibrinogen, and whole-blood viscosity, and insulin sensitivity in healthy humans. Twenty-one 21-year-old men were studied with the hyperinsulinemic euglycemic glucose clamp technique. We...
Tags: Insulin (Regular), Fibrinogen, Whole blood viscosity (WBV), Shear rate, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)
Effects of Long-Acting Propranolol and Verapamil on Blood Pressure, Platelet Function, Metabolic and Rheological Properties in Hypertension.
The newly developed antihypertensive drugs, the long-acting beta-blocker propranolol and the sustained release calcium antagonist verapamil, arecompared in their antihypertensive, platelet function, rheological properties and metabolic effects. The trial was a double-blind, randomised, placebo-...
Tags: Verapamil, Propranolol, Plasma viscosity (PV), Whole blood viscosity (WBV), Fibrinogen, Erythrocyte deformability, Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C), Platelets (or thrombocytes), Lipids, Platelet activation, Platelet aggregation
Effects of Omega-3 Polyunsaturated Fatty Acids on Plasma Indices of Thrombogenesis and Inflammation in Patients Post-Myocardial Infarction.
OBJECTIVE: To determine the effects of n-3 PUFAs supplementation on plasma indices of coagulation (fibrinogen), fibrin D-Dimer (an index ofthrombogenesis and fibrin turnover), endothelial damage/dysfunction (von Willebrand factor (vWf)), platelet activation (soluble P-selectin (sP-sel))...
Tags: Omega-3-acid Ethyl Esters, Total cholesterol, Low-density lipoprotein cholesterol (LDL-C), Triglycerides, P-selectin, Platelet activation, von Willebrand factor (vWF), Fibrinogen, Inflammation, Lipids, Plasma proteins