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BACKGROUND: Coronary heart disease (CHD) is the leading cause of mortality in women, with an incidence that increases after menopause, hencesuggesting a cardioprotective role of oestrogen. Menopause also results in a decline in androgen levels with resulting symptoms of decreased libido and...
Tags: Esterified Estrogens, Methyltestosterone, Plasma viscosity (PV), Fibrinogen, Total cholesterol, Triglycerides, High-density lipoprotein cholesterol (HDL-C)
Effects of Hormone Replacement Therapies on Fibrinogen and Plasma Viscosity in Postmenopausal Women.
In women, cardiovascular morbidity and mortality sharply increase after the onset of menopause. There is substantial evidence that hormone replacement therapy (HRT) may decrease the risk of coronary heart disease (CHD); however, the mechanisms of this preventive effect are unclear. We...
Tags: Estrogens (conjugated), Estrogens (conjugated) and medroxyprogesterone, Plasma viscosity (PV), Fibrinogen
Haemorheological Disturbances in Hypertensive Type 2 Diabetic Patients -- Influence of Antihypertensive Therapy.
Haemorheological changes have been described in hypertension as well as in diabetes mellitus. Antihypertensive treatment improves rheology inhypertensive patients. The aim of this study was to describe the haemorheological profile and its impact on shear stress in hypertensive type 2 diabetes...
Tags: Enalapril, Amlodipine, Whole blood viscosity (WBV), Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Fibrinogen, Shear stress (or wall shear stress WSS, endothelial shear stress ESS, vascular shear stress)
C-reactive protein (CRP) levels were measured in 105 patients with rheumatoid arthritis (RA) during treatment with slow-acting anti-rheumatoid drugsD-penicillamine, alclofenac, hydroxychloroquine, gold, sulphasalazine and azathioprine. A control group treated with aspirin alone was also included....
Tags: Hydroxychloroquine, C-reactive protein (CRP), Fibrinogen, Erythrocyte sedimentation rate (ESR)
Hormone Replacement Therapy Improves Cardiovascular Risk by Lowering Plasma Viscosity in Postmenopausal Women.
Hormone replacement therapy may protect against cardiovascular disease through several mechanisms that have variable actions on the majordeterminants of plasma viscosity. Plasma viscosity is an important predictor of incident and recurrent cardiovascular events and mortality in coronary heart...
The effect of simvastatin in 27 patients with severe primary hypercholesterolaemia was assessed by a double-blind placebo controlled parallel grouptrial. Total serum cholesterol, LDL-cholesterol and apoprotein B (ApoB) were significantly reduced by simvastatin 40 mg daily. Reductions...
Tags: Simvastatin, Total cholesterol, Low-density lipoprotein cholesterol (LDL-C), Very low-density lipoprotein cholesterol (VLDL-C), High-density lipoprotein cholesterol (HDL-C), Apolipoprotein A-I (apo A-I), Apolipoprotein B (ApoB), Triglycerides, Fibrinogen, Plasma viscosity (PV), Whole blood viscosity (WBV)
To assess the effect of lovastatin on blood rheology, the hemorheological determinants fibrinogen, red cell aggregation, plasma viscosity, hematocrit and platelet aggregation (spontaneous and ADP-induced) were studied in 15 patients with type II hyperlipoproteinemia in the course of treatment...
Tags: Lovastatin, Fibrinogen, Erythrocyte aggregation (RBC aggregation), Plasma viscosity (PV), Total cholesterol, Triglycerides, Platelet aggregation, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)
Effects of Doxazosin on Hemorheological, Hemodynamic and Lipid Parameters in Patients With Essential Hypertension.
It is known from previous studies that hemorheological parameters are altered in patients with essential hypertension. The hemorheological and hemodynamical effects of doxazosin, a selective alpha-1-adrenoreceptor blocker agent, was examined in twenty patients (mean age: 54+/-10 years) with...
Tags: Doxazosin, Whole blood viscosity (WBV), Lipids, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Fibrinogen, Total cholesterol, Triglycerides, Adjusted whole blood viscosity (or hematocrit-corrected blood viscosity, normalized for Hct), Plasma viscosity (PV)
Blood Rheology, Cardiovascular Risk Factors, and Cardiovascular Disease: The West of Scotland Coronary Prevention Study.
The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an average of 4.9 years. We hypothesised...
Tags: Heart Disease, Coronary heart disease (CHD), Ischemic heart disease (IHD), Coronary artery disease (CAD), Myocardial Infarction, Pravastatin, Plasma viscosity (PV), Whole blood viscosity (WBV), Fibrinogen, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), White blood cells (WBC) (or leukocytes)
A Placebo-Controlled, Double-Blind Study of Eicosapentaenoic Acid-Rich Fish Oil in Patients With Stable Angina Pectoris.
A study was carried out to evaluate the clinical and haematological effects of dietary supplementation with eicosapentaenoic acid (EPA)-rich fish oil(MaxEPA', 2.8 g EPA daily) compared to placebo (olive oil) in 10 patients with stable angina pectoris. After 3 months, there was a significant...
Tags: Omega-3-acid Ethyl Esters, Erythrocyte deformability, Whole blood viscosity (WBV), Plasma viscosity (PV), Platelet aggregation, Fibrinogen, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)