You are here
Lipid-Modifying and Pleiotropic Effects of Gemfibrozil, Simvastatin and Pravastatin in Patients With Dyslipidemia.
AIM: To assess the lipid-modifying and pleiotropic effects of drugs of the statin group (simvastatin and pravastatin) and the fibrate group (gemfibrozil) in dyslipidemia patients. PATIENTS AND METHODS: Fifty eight patients with primary dysli pidemia were recruited for a 12-week treatment. Forty...
Tags: Gemfibrozil, Pravastatin, Simvastatin, Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Total cholesterol, Low-density lipoprotein cholesterol (LDL-C), Apolipoprotein A-I (apo A-I), Lipids, Antithrombin III, Triglycerides, High-density lipoprotein cholesterol (HDL-C), Apolipoprotein B (ApoB), Platelet aggregation, Platelet factor 4 (PF4), Platelets (or thrombocytes), α2-macroglobulins, Fibrinogen
Failure of Pentoxifylline or Cilostazol to Improve Blood and Plasma Viscosity, Fibrinogen, and Erythrocyte Deformability in Claudication.
Peripheral artery disease is associated with altered blood rheologic properties, including increased viscosity and decreased red blood cell (RBC)deformability. Pentoxifylline and cilostazol are available therapies for intermittent claudication. Improvement of blood viscosity and erythrocyte...
Tags: Cilostazol, Pentoxifylline, Whole blood viscosity (WBV), Lipids, Erythrocyte deformability, Fibrinogen, Erythrocyte sedimentation rate (ESR), Plasma viscosity (PV)
A clinical investigation was undertaken of the haemorheological effects of short-term administration of synthetic sex hormones. In a randomisedcontrolled investigative trial, groups of 20 women taking ethynyloestradiol, norethisterone, combined norgestrel and ethynyloestradiol or no therapy had...
Tags: Ethinyl Estradiol and Norgestrel, Norethindrone, Whole blood viscosity (WBV), Fibrinogen, Erythrocyte deformability, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)
Effect of a High-Fructose Diet on Glucose Tolerance, Plasma Lipid and Hemorheological Parameters During Oral Contraceptive Administration in Female Rats.
Oral contraceptive (OC) use and increased fructose feeding have been associated with altered cardiometabolic effects. The effect of increased dietaryfructose during OC use on cardiometabolic parameters is unknown. We investigated the effects of a high-fructose diet on body weight gain, fasting...
Tags: Ethinyl Estradiol and Norgestrel, Whole blood viscosity (WBV), Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), High-density lipoprotein cholesterol (HDL-C), Fibrinogen, Blood glucose, Triglycerides, Lipids
The role of hemostatic variables (which promote hemostatic plugs and thrombi) and rheological variables (which affect blood flow) in the pathogenesisof vascular diseases (ischemic heart disease, stroke, and peripheral arterial disease) is reviewed, with emphasis on epidemiological studies....
Tags: Pravastatin, Fibrinogen, Plasma viscosity (PV), Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), von Willebrand factor (vWF), White blood cells (WBC) (or leukocytes)
A Controlled Trial of the Effect of Folate Supplements on Homocysteine, Lipids and Hemorheology in End-Stage Renal Disease.
Elevated plasma homocysteine (Hcy), dyslipidemia and hemorheological abnormalities all occur commonly in end-stage renal disease (ESRD) and are recognized risk factors for arteriosclerosis. To study the effect of folate supplementation on these factors we conducted a randomized controlled trial....
Tags: Folic acid, Plasma viscosity (PV), Fibrinogen, Total cholesterol, Triglycerides, Low-density lipoprotein cholesterol (LDL-C), Platelet aggregation
Effect of Atorvastatin on Hemorheologic-Hemostatic Parameters and Serum Fibrinogen Levels in Hyperlipidemic Patients.
Plasma fibrinogen and hemorheologic-hemostatic factors contribute to dyslipidemia-induced morbidity. Some of these parameters can be favorablyaffected when abnormal serum lipoprotein levels are corrected. Thus, we investigated whether treatment with atorvastatin would result in changes inplasma...
Tags: Atorvastatin, Fibrinogen, High-density lipoprotein cholesterol (HDL-C), Low-density lipoprotein cholesterol (LDL-C), Platelet aggregation, Triglycerides, Plasma viscosity (PV), Erythrocyte sedimentation rate (ESR)
A Pilot Study to Test The Effect of Pulsatile Insulin Infusion on Cardiovascular Mechanisms That Might Contribute to Attenuation of Renal Compromise in Type 1 Diabetes Mellitus Patients With Proteinuria.
We hypothesized that correction of insulin deficiency by pulsatile intravenous insulin infusion in type 1 diabetes mellitus patients with nephropathy preserves renal function by mechanisms involving cardiac autonomic function, cardiac mass, or efficiency, or by hemostatic mechanisms. The control...
Tags: Insulin (Regular), Plasma viscosity (PV), Plasminogen activator inhibitor-1 (PAI-1), Platelet aggregation, Fibrinogen, Hemoglobin (Hgb), von Willebrand factor (vWF)
To determine the hemorheological effects of oral contraceptives, 50 healthy young women took no medication for 3 cycles. Subsequently they were randomized into group A and B. Group A took Diane-35, B took Microgynon each for 6 cycles. Finally 3 cycles without medication followed. Blood viscosity...
Tags: Ethinyl Estradiol and Levonorgestrel, Ethinyl Estradiol and Gestodene, Fibrinogen, Plasma viscosity (PV), Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Red cell filterability
OBJECTIVE: To determine the effect of transdermal oestrogen replacement therapy on the haemostatic balance of menopausal women. DESIGN: Open, parallel group, prospective study. SETTING: Three hospital-based menopause clinics. SUBJECTS: Fifty-two postmenopausal women receiving transdermal hormone...