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Effect of Medication With Pravastatin Sodium on Hemorheological Parameters in Patients With Hyperlipoproteinemia.
Pravastatin sodium, a newly developed potent synthesis inhibitor of HMG-CoA (beta-hydroxy-beta-methylglutaryl-cocarboxylase-A) reductase(Sankyo Co., Ltd., Japan) was medicated, 10 approximately 15 mg/day (mean: 11.1 mg/day) for 10.2 weeks in mean, in 14 patients with primaryhyperlipoproteinemia...
Tags: Pravastatin, Total cholesterol, High-density lipoprotein cholesterol (HDL-C), Whole blood viscosity (WBV), Fibrinogen, Adjusted whole blood viscosity (or hematocrit-corrected blood viscosity, normalized for Hct)
Altered Flow Properties of Blood and Increased Plasma Fibrinogen in Cyclosporin-Treated Renal Allograft Recipients.
BACKGROUND: Abnormalities in blood rheology may be factors contributing to cardiovascular complications and the progression of renal failure inkidney allograft recipients. The haemorheological variables haematocrit, fibrinogen, whole blood viscosity, plasma viscosity, erythrocyte...
Tags: Cyclosporine, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Fibrinogen, Plasma viscosity (PV), Whole blood viscosity (WBV), Erythrocyte aggregation (RBC aggregation), Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C), Total cholesterol, Triglycerides
Lovastatin Therapy in Hypercholesterolemia: Effect on Fibrinogen, Hemorrheologic Parameters, Platelet Activity, and Red Blood Cell Morphology.
The effect of lovastatin therapy on blood rheology was investigated in 26 hypercholesterolemic patients. Treatment with lovastatin was associated with a significant improvement in whole blood filtration time and a tendency toward normalization in red blood cell morphology. A significant increase...
Tags: Lovastatin, Fibrinogen, Platelet aggregation, Platelets (or thrombocytes), Whole blood viscosity (WBV), Plasma viscosity (PV)
Effects of Acute Insulin-Induced Hypoglycaemia on Haemostasis, Fibrinolysis and Haemorheology in Insulin-Dependent Diabetic Patients and Control Subjects.
1. The effects of acute hypoglycaemia on haemostasis, fibrinolysis, blood viscosity and erythrocyte aggregation were examined after acute insulin-induced hypoglycaemia in six normal male subjects and in six male patients with poorly controlled insulin-dependent diabetes. In the control...
Tags: Insulin (Regular), Whole blood viscosity (WBV), Fibrinogen, Plasminogen, von Willebrand factor (vWF), Erythrocyte aggregation (RBC aggregation)
Effects of Felodipine ER and Hydrochlorothiazide on Blood Rheology in Essential Hypertension--A Randomized, Double-Blind, Crossover Study.
The haemorheological effects of felodipine extended release (ER), a new dihydropyridine calcium antagonist, were compared withhydrochlorothiazide (HCTZ) in 28 mild to moderate hypertensives (18 men and 10 women, aged 30-70 years) in a randomized, double-blind,crossover trial. Antihypertensive...
Tags: Felodipine, Hydrochlorothiazide, Whole blood viscosity (WBV), Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Erythrocyte aggregation (RBC aggregation), Erythrocyte deformability, Fibrinogen
Primary Chylomicronemia in Patients With Severe Familial Hypertriglyceridemia Responds to Long-Term Treatment With (n-3) Fatty Acids.
Because it disturbs microcirculation, chylomicronemia can cause severe clinical complications such as acute pancreatitis. Dietary measures are very important in the prevention and treatment of this condition. Dietary supplementation with (n-3) fatty acids has been shown to be of benefit in short-...
Tags: Omega-3-acid Ethyl Esters, Triglycerides, Plasma viscosity (PV), Chylomicrons, Apolipoprotein B (ApoB), Lipids, Fibrinogen
Haemorheological and Endothelial-Dependent Alterations in Heart Failure After ACE Inhibitor, Calcium Antagonist and Beta Blocker.
The aim of our study was to evaluate endothelium-dependent dilatation induced by an ACE-inhibitor, calcium antagonist and beta blocker in patientssuffering from heart failure (NYHA class II and III). We studied 34 patients (19M, 15F, mean age 76.96+/-8.82) in pharmacological wash-out for at least...
Tags: Ramipril, Carvedilol, Amlodipine, Whole blood viscosity (WBV), Fibrinogen, Plasminogen activator inhibitor-1 (PAI-1), Platelet aggregation
A Randomized Comparison of the Effects of Aspirin and Clopidogrel on Thrombotic Risk Factors and C-Reactive Protein Following Myocardial Infarction: the CADET Trial.
A randomized, double-blind multicenter trial-the Clopidogrel and Aspirin: Determination of the Effects on Thrombogenicity (CADET) trial-was carriedout to compare the effects of clopidogrel vs. aspirin on thrombotic variables and C-reactive protein (CRP), over a 6-month period of treatment, in...
Tags: Clopidogrel, C-reactive protein (CRP), Fibrinogen, von Willebrand factor (vWF), Plasma viscosity (PV)
Effects of N-3 Fatty Acids and Fenofibrate on Lipid and Hemorrheological Parameters in Familial Dysbetalipoproteinemia and Familial Hypertriglyceridemia.
There is increasing evidence that hemorrheological abnormalities are associated with an enhanced risk of atherosclerosis. The n-3 fatty acids (n-3-FA) have been shown to have beneficial effects on atherosclerosis in patients with dyslipoproteinemias. We studied 23 patients with elevated plasma...
Tags: Fenofibrate, Omega-3-acid Ethyl Esters, Lipids, Whole blood viscosity (WBV), Shear rate, Plasma viscosity (PV), Fibrinogen, Erythrocyte aggregation (RBC aggregation), Very low-density lipoprotein cholesterol (VLDL-C)
Influence of Atorvastatin Versus Simvastatin on Fibrinogen and Other Hemorheological Parameters in Patients With Severe Hypercholesterolemia Treated With Regular Low-Density Lipoprotein Immunoadsorption Apheresis.
Low-density lipoprotein (LDL) apheresis is a treatment option in patients with coronary artery disease and elevated LDL cholesterol concentrations ifmaximal drug therapy fails to achieve adequate LDL cholesterol reduction. This therapy is more effective when combined with strong lipid-lowering...
Tags: Atorvastatin, High-density lipoprotein cholesterol (HDL-C), Low-density lipoprotein cholesterol (LDL-C), Plasma viscosity (PV), Whole blood viscosity (WBV), Red cell filterability, Fibrinogen, Erythrocyte aggregation (RBC aggregation)