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Effects of Long-Acting Propranolol and Verapamil on Blood Pressure, Platelet Function, Metabolic and Rheological Properties in Hypertension.
The newly developed antihypertensive drugs, the long-acting beta-blocker propranolol and the sustained release calcium antagonist verapamil, arecompared in their antihypertensive, platelet function, rheological properties and metabolic effects. The trial was a double-blind, randomised, placebo-...
Tags: Verapamil, Propranolol, Plasma viscosity (PV), Whole blood viscosity (WBV), Fibrinogen, Erythrocyte deformability, Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C), Platelets (or thrombocytes), Lipids, Platelet activation, Platelet aggregation
Administration of Dietary Fish Oil Capsules in Healthy Middle-Aged Japanese Men With a High Level of Fish Consumption.
The nutritional effects of fish oil, which is rich in the n-3 polyunsaturated fatty acids, have been reported. In this randomized, placebo-controlled,double-blind, crossover study, we evaluated the effects of dietary fish oil capsules on the hematological parameters of healthy middle-aged...
Tags: Omega-3-acid Ethyl Esters, Whole blood viscosity (WBV), Total cholesterol, Plasma proteins, Low-density lipoprotein cholesterol (LDL-C), Lipids
Effect of Omega-3 Fatty Acids in Diet of Type I Diabetic Subjects on Lipid Values and Hemorheological Parameters.
Twelve type I (insulin-dependent) diabetic subjects in stable metabolic control for at least 3 mo received a controlled diet containing 50%carbohydrate, 35% fat, and 15% protein. Calorie intake varied from 1800 to 2200 calories, depending on individual needs. Part of the polyunsaturatedomega-6...
Tags: Omega-3-acid Ethyl Esters, Plasma viscosity (PV), Whole blood viscosity (WBV), Lipids, Triglycerides, High-density lipoprotein cholesterol (HDL-C)
Lovastatin Therapy in Heterozygous Familial Hypercholesterolaemic Patients: Effect on Blood Rheology and Fibrinogen Levels.
Thirteen heterozygous familial hypercholesterolaemic patients were treated with lovastatin for 1 year, and were investigated for the effect on lipid profile, blood rheology and fibrinogen levels. A significant dose-dependent reduction in serum levels of total and LDL-cholesterol, Apo B and the...
Tags: Lovastatin, High-density lipoprotein cholesterol (HDL-C), Low-density lipoprotein cholesterol (LDL-C), Apolipoprotein B (ApoB), Lipids, Total cholesterol, Fibrinogen, Red cell filterability
Effects of Atorvastatin Versus Fenofibrate on Lipoprotein Profiles, Low-Density Lipoprotein Subfraction Distribution, and Hemorheologic Parameters in Type 2 Diabetes Mellitus With Mixed Hyperlipoproteinemia.
Diabetic dyslipoproteinemia characterized by hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol, and often elevated low-density lipoprotein (LDL) cholesterol with predominance of small, dense LDL is a strong risk factor for atherosclerosis. It is unclear whether fibrate or...
Tags: Fenofibrate, Atorvastatin, Lipids, Fibrinogen, Plasma viscosity (PV), Erythrocyte aggregation (RBC aggregation), Triglycerides, High-density lipoprotein cholesterol (HDL-C), Low-density lipoprotein cholesterol (LDL-C)
Reports suggest that the low incidence of ischaemic heart disease in Greenlandic Eskimos is related to the effect of a diet rich in eicosapentaenoicacid on platelet reactivity and plasma lipid concentrations. A double blind randomised investigation was therefore conducted of the effects on...
Tags: Omega-3-acid Ethyl Esters, Platelet activation, Whole blood viscosity (WBV), Triglycerides, Lipids
Relationship Between Plasma Essential Fatty Acids and Smoking, Serum Lipids, Blood Pressure and Haemostatic and Rheological Factors.
We aimed to determine whether levels of plasma fatty acids are correlated with other potential risk factors for cardiovascular disease, using a sampleof patients from a cross-sectional survey of the general population, in the City of Edinburgh. 306 men and women aged 55-74 years of whom half...
Tags: Omega-3-acid Ethyl Esters, Plasma viscosity (PV), Whole blood viscosity (WBV), Lipids, Triglycerides, Fibrinogen, High-density lipoprotein cholesterol (HDL-C)
Effect of Low-Dose Oral Triphasic Contraceptives on Blood Viscosity, Coagulation and Lipid Metabolism.
The purpose of the study was to determine the relationship between hemorheological profile, i.e. blood viscosity, and other risk factors for cardiovascular and thrombotic diseases in women taking oral contraceptives and if blood viscosity may be considered a marker of cardiovascular risk in OC...
Tags: Ethinyl Estradiol and Gestodene, Plasma viscosity (PV), Whole blood viscosity (WBV), Lipids, High-density lipoprotein cholesterol (HDL-C), Apolipoprotein A-I (apo A-I), Fibrinogen, Erythrocyte deformability
Capillary Microscopy and Hemorheology in Children During Antiepileptic Monotherapy With Carbamazepine and Valproate.
The interactions of epilepsy and antiepileptic therapy an one hand and cardiovascular system on the other hand are multiple and complex. Antiepileptic drugs (AEDs) cause alterations of serum lipids and of the fatty acid composition of the membranes. Homocystein, known to induce vascular...
Tags: Divalproex, Carbamazepine, Erythrocyte aggregation (RBC aggregation), Lipids, Plasma viscosity (PV)
Effects of Fish Oil Capsules in Two Dosages on Blood Pressure, Platelet Functions, Haemorheological and Clinical Chemistry Parameters in Apparently Healthy Subjects.
The effects of a fish oil concentrate with an omega-3 fatty acid content of 42% was determined in two dosages in a double-blind, placebo-controlledstudy with a parallel group comparison over a period of 5 weeks with 30 healthy subjects. The daily intake chosen was four and eight...
Tags: Omega-3-acid Ethyl Esters, Lipids, Plasma proteins, Plasma viscosity (PV), Erythrocyte deformability