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Effects of Fish Oil Capsules in Two Dosages on Blood Pressure, Platelet Functions, Haemorheological and Clinical Chemistry Parameters in Apparently Healthy Subjects.
The effects of a fish oil concentrate with an omega-3 fatty acid content of 42% was determined in two dosages in a double-blind, placebo-controlledstudy with a parallel group comparison over a period of 5 weeks with 30 healthy subjects. The daily intake chosen was four and eight...
Tags: Omega-3-acid Ethyl Esters, Lipids, Plasma proteins, Plasma viscosity (PV), Erythrocyte deformability
Plasma Viscosity in Female Patients With Hypothyroidism: Effects of Oxidative Stress and Cholesterol.
Hypothyroidism is associated with atherosclerotic events, however, the mechanism is unclear. We investigated the effects of oxidative stress andcholesterol on plasma viscosity in female patients with hypothyroidism (n = 20; mean age: 45.5 +/- 5.5 years) at baseline and after L-...
A Comparison of the Effect of Frusemide and Bumetanide on the Diuretic Response and Fibrinolytic Mechanism in Man.
A double-blind, crossover trial has compared the diuretic response of ten normal male subjects to the oral administration of frusemide (40 mg) and bumetanide (1 mg). Both drugs gave a similar profile, with acute onset and cessation of response, and a marked peak effect. There was no significant...
Tags: Bumetanide, Plasma proteins, Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)
Effects of Fish-Oil Ingestion on Cardiovascular Risk Factors in Hyperlipidemic Subjects in Israel: A Randomized, Double-Blind Crossover Study.
Effects of a daily fish-oil supplement on serum lipids, apolipoproteins, and some platelet functions and hemorheologic variables were examined in 27hyperlipidemic subjects in a randomized, controlled, double-blind, crossover fashion with an identically encapsulated vegetable oil serving as...
Tags: Omega-3-acid Ethyl Esters, Triglycerides, Lipids, Plasma proteins, High-density lipoprotein cholesterol (HDL-C), Plasma viscosity (PV)
The Effect of Diuretics on Red Blood Cell Microrheological Parameters in Female Hypertensive Patients.
This study was designed to examine changes of hemorheological parameters and red cell aggregation particularly in essential arterial hypertensionsubjects receiving antihypertensive diuretic therapy. Fifty six female subjects were enrolled in this study. Thirty seven subjects (group I) were...
Tags: Hydrochlorothiazide, Furosemide, Erythrocyte aggregation (RBC aggregation), Erythrocyte deformability, Plasma proteins, Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)
Effects of Pravastatin Sodium and Simvastatin on Plasma Fibrinogen Level and Blood Rheology in Type II Hyperlipoproteinemia.
Elevated plasma fibrinogen level is known to progress atherosclerosis and to be one of the risk factors for the occurrence of cardiovascular diseases. The objective of this study is to evaluate the changes in plasma fibrinogen level and blood rheology in patients with type II...
Tags: Pravastatin, Simvastatin, Fibrinogen, Total cholesterol, Whole blood viscosity (WBV), Plasma viscosity (PV), Adjusted whole blood viscosity (or hematocrit-corrected blood viscosity, normalized for Hct), Shear rate, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Plasma proteins, Albumin
The possible antiatherogenic action of eicosapentaenoic acid (EPA) was pharmacologically investigated using purified and ethylesterified fish oilcontaining 75% EPA (EPA-E) in multiple oral doses in rats and rabbits. EPA-E showed dose-dependent prevention of thrombus formation in a vascular shunt...
Effects of Omega-3 Polyunsaturated Fatty Acids on Plasma Indices of Thrombogenesis and Inflammation in Patients Post-Myocardial Infarction.
OBJECTIVE: To determine the effects of n-3 PUFAs supplementation on plasma indices of coagulation (fibrinogen), fibrin D-Dimer (an index ofthrombogenesis and fibrin turnover), endothelial damage/dysfunction (von Willebrand factor (vWf)), platelet activation (soluble P-selectin (sP-sel))...
Tags: Omega-3-acid Ethyl Esters, Total cholesterol, Low-density lipoprotein cholesterol (LDL-C), Triglycerides, P-selectin, Platelet activation, von Willebrand factor (vWF), Fibrinogen, Inflammation, Lipids, Plasma proteins
The Short-Term Effect of Intravenous Nitroglycerin on Haematocrit; an Additional Benefit in Patients With Myocardial Ischaemia?
Organic nitrates exert their effect by direct inhibition of vascular tone, resulting in decreased myocardial oxygen demand and improved oxygen supply. Less well known is the effect of nitrates on blood rheology. To evaluate the haemodiluting effect of intravenous nitroglycerin we studied 70...
Tags: Nitroglycerin, Albumin, Hemoglobin (Hgb), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Plasma proteins
Effects of Furosemide on Hemorheologic Alterations Induced by Incremental Treadmill Exercise in Thoroughbreds.
OBJECTIVE: To determine whether furosemide treatment altered the blood flow properties and serum and RBC electrolyte concentrations of Thoroughbreds during submaximal treadmill exercise. DESIGN: Thoroughbreds were subjected to submaximal treadmill exercise with and without treatment with...
Tags: Furosemide, Mean corpuscular volume (MCV) (or mean cell volume, mean erythrocyte volume), Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Plasma proteins, Red cell filterability