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Haemorheological and Endothelial-Dependent Alterations in Heart Failure After ACE Inhibitor, Calcium Antagonist and Beta Blocker.
The aim of our study was to evaluate endothelium-dependent dilatation induced by an ACE-inhibitor, calcium antagonist and beta blocker in patientssuffering from heart failure (NYHA class II and III). We studied 34 patients (19M, 15F, mean age 76.96+/-8.82) in pharmacological wash-out for at least...
Tags: Ramipril, Carvedilol, Amlodipine, Whole blood viscosity (WBV), Fibrinogen, Plasminogen activator inhibitor-1 (PAI-1), Platelet aggregation
Improved Insulin Sensitivity by the Angiotensin II-Receptor Blocker Losartan is Not Explained by Adipokines, Inflammatory Markers, or Whole Blood Viscosity.
We have previously found improved insulin sensitivity after antihypertensive treatment with an angiotensin II-receptor blocker as compared with acalcium channel blocker in hypertensives. In this study, we compare the effect of these 2 principal different vasodilating agents on levels of...
Tags: Losartan, Amlodipine, Whole blood viscosity (WBV), Plasminogen activator inhibitor-1 (PAI-1), Tumor necrosis factor alpha (TNFα), Inflammation, C-reactive protein (CRP)
A Pilot Study to Test The Effect of Pulsatile Insulin Infusion on Cardiovascular Mechanisms That Might Contribute to Attenuation of Renal Compromise in Type 1 Diabetes Mellitus Patients With Proteinuria.
We hypothesized that correction of insulin deficiency by pulsatile intravenous insulin infusion in type 1 diabetes mellitus patients with nephropathy preserves renal function by mechanisms involving cardiac autonomic function, cardiac mass, or efficiency, or by hemostatic mechanisms. The control...
Tags: Insulin (Regular), Plasma viscosity (PV), Plasminogen activator inhibitor-1 (PAI-1), Platelet aggregation, Fibrinogen, Hemoglobin (Hgb), von Willebrand factor (vWF)
Effects of Acute Insulin-Induced Hypoglycaemia on Haemostasis, Fibrinolysis and Haemorheology in Insulin-Dependent Diabetic Patients and Control Subjects.
1. The effects of acute hypoglycaemia on haemostasis, fibrinolysis, blood viscosity and erythrocyte aggregation were examined after acute insulin-induced hypoglycaemia in six normal male subjects and in six male patients with poorly controlled insulin-dependent diabetes. In the control...
Tags: Insulin (Regular), Whole blood viscosity (WBV), Fibrinogen, Plasminogen, von Willebrand factor (vWF), Erythrocyte aggregation (RBC aggregation)