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  AIM: To compare the effects of an angiotensin converting enzyme (ACE) inhibitor and a thiazide diuretic on platelet function and haemorrheologicalvariables, since these factors may contribute to the atherosclerotic and thrombotic complications associated with hypertension. METHODS: Following a 2-...
Type: Abstracts
  Haemorheological changes have been described in hypertension as well as in diabetes mellitus. Antihypertensive treatment improves rheology inhypertensive patients. The aim of this study was to describe the haemorheological profile and its impact on shear stress in hypertensive type 2 diabetes...
Type: Abstracts
  1. The shear stress of flowing blood profoundly influences the release of endothelium-dependent vasodilative and constrictive factors. Conversely, the influence of these mediators such as nitric oxide (NO) or endothelin-1 (ET-1) on blood rheology remains elusive. In the present study the...
Type: Abstracts
  The aim of the present study was to determine whether changes of carotid wall shear stress induced by changes in blood viscosity after diureticadministration cause carotid arterial dilatation in elderly hypertensives, as reported in the cat. Arterial wall shear rate (ultrasound technique,...
Type: Abstracts
  Pravastatin has neuroprotective effects against aging but its role in brain injury remains unclear. This study evaluated the effects of pravastatin on theultrastructural changes and hemorheological parameters in rats after traumatic brain injury (TBI) of right parietal cortical contusion by a...
Type: Abstracts
  BACKGROUND AND PURPOSE: Despite speculations, it is unknown whether statins affect wall shear stress (WSS). Therefore, the effect ofpravastatin on WSS was investigated. METHODS: In 355 elderly individuals participating in the PROSPER study (follow up after 3 years), the effect of 40 mg...
Type: Abstracts

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