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  Plasma fibrinogen concentration and whole-blood viscosity, the latter measured at two shear rates (23 and 230 sec-1), were estimated during eight episodes of sickle-cell crisis and compared with values in 26 sickle-cell anaemia patients who were not in crisis. Painful crisis was associated with a...
Type: Abstracts
  BACKGROUND: Recent evidence suggests that autonomic nervous system activity could be involved in the pathophysiology of sickle cell disease, but it is unclear whether differences in autonomic nervous system activity are detectable during steady state in patients with mild and severe disease. The...
Type: Abstracts
  Abnormal rheologic behavior of sickle cells is the result of increased viscosity of the blood caused by the polymerization of hemoglobin S and the resultant production of dense, dehydrated sickle erythrocytes. As the viscosity of sickle cells increases, there is a negative impact on blood flow,...
Type: Abstracts

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