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  AIM: To compare the effects of an angiotensin converting enzyme (ACE) inhibitor and a thiazide diuretic on platelet function and haemorrheologicalvariables, since these factors may contribute to the atherosclerotic and thrombotic complications associated with hypertension. METHODS: Following a 2-...
Type: Abstracts
  Haemorheological changes have been described in hypertension as well as in diabetes mellitus. Antihypertensive treatment improves rheology inhypertensive patients. The aim of this study was to describe the haemorheological profile and its impact on shear stress in hypertensive type 2 diabetes...
Type: Abstracts
  Pravastatin has neuroprotective effects against aging but its role in brain injury remains unclear. This study evaluated the effects of pravastatin on theultrastructural changes and hemorheological parameters in rats after traumatic brain injury (TBI) of right parietal cortical contusion by a...
Type: Abstracts
  BACKGROUND AND PURPOSE: Despite speculations, it is unknown whether statins affect wall shear stress (WSS). Therefore, the effect ofpravastatin on WSS was investigated. METHODS: In 355 elderly individuals participating in the PROSPER study (follow up after 3 years), the effect of 40 mg...
Type: Abstracts
  1. The shear stress of flowing blood profoundly influences the release of endothelium-dependent vasodilative and constrictive factors. Conversely, the influence of these mediators such as nitric oxide (NO) or endothelin-1 (ET-1) on blood rheology remains elusive. In the present study the...
Type: Abstracts
  The aim of the present study was to determine whether changes of carotid wall shear stress induced by changes in blood viscosity after diureticadministration cause carotid arterial dilatation in elderly hypertensives, as reported in the cat. Arterial wall shear rate (ultrasound technique,...
Type: Abstracts
  Episodes of psychological and physical stress may elicit thrombotic cardiac events, such as myocardial infarction. These events are triggered when there are concurrent hemodynamic, hemostatic, and endothelial abnormalities. Hemodynamic, hemostatic, and endothelial reactions of 72 (15 women, 57...
Type: Abstracts
  The mechanisms for stress-induced changes in hematocrit and blood viscosity are unclear. Twenty-two males completed experimental (30 min baseline, 10 min mental stress, 30 min recovery) and no-stress control conditions (70 min). Hemostatic and hemodynamic activity were measured throughout....
Type: Abstracts
  We studied effects of mental stress on whole-blood viscosity (WBV) and blood pressure (BP), and relations between WBV and autonomic nervoussystem activity and insulin sensitivity. We measured WBV (rotational rheometer), plasma noradrenaline (NA), finger BP, heart rate variability (HRV) and...
Type: Abstracts
  In this study, we examined the effects of acute psychological stress on hemorheology and hemoconcentration in humans and the associations between stress-induced cardiovascular reactivity and hemorheological changes. Stress-induced changes in hemorheology and hemorheological changes were assessed...
Type: Abstracts

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