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   BACKGROUND: Major depressive disorder (MDD) is an independent risk factor for cardiovascular disease (CVD); the presence of MDD symptoms in patients with CVD is associated with a higher incidence of cardiac complications following acute myocardial infarction (MI). Stress-hemoconcentration, a...
Type: Abstracts
  The effects of furosemide and pentoxifylline on blood flow properties in horses were investigated. Hematologic and rheologic changes were examined in 4 horses before and 3 minutes after administration of epinephrine (1 mg, IV). The next day, hemorheologic changes were determined before and 3...
Type: Abstracts
  The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an average of 4.9 years. We hypothesised...
Type: Abstracts
  Previous studies have explored the association between hemorheologic alterations and aspirin resistance, pointing out the possible interactionbetween hematologic components and platelet responsiveness to antiplatelet drugs. The aim of this study was to evaluate the association...
Type: Abstracts
  The role of hemostatic variables (which promote hemostatic plugs and thrombi) and rheological variables (which affect blood flow) in the pathogenesisof vascular diseases (ischemic heart disease, stroke, and peripheral arterial disease) is reviewed, with emphasis on epidemiological studies....
Type: Abstracts
  AIMS: In humans, little is known about the effects of platelet-leucocyte interactions on blood viscosity and microvascular perfusion. This study testedthe hypotheses that (1) activation and interactions between platelets and leucocytes may have an impact on microvascular blood viscosity...
Type: Abstracts
  BACKGROUND:  Different antihypertensive therapies may exert benefits via not only a reduction in blood pressure but also in improving the risk of thrombosis. METHODS: We tested the hypothesis that a more modern antihypertensive drug regimen (ie, amlodipine +/- perindopril) would have a more...
Type: Abstracts
  Recently the phenomenon of aspirin resistance has been object of several studies, but no data are available on the possible role of thehaemorheologic parameters in affecting platelet function and resistance to antiplatelet agents. Aim of our study was to evaluate platelet function and...
Type: Abstracts
  OBJECTIVES: To report the effects of the anti-oestrogen tamoxifen on biochemical and haematological parameters. DESIGN: Randomized, double-blind comparison of tamoxifen 20 mg per day and placebo, over two years. SETTING: A university hospital. SUBJECTS: Forty-six healthy late-postmenopausal women...
Type: Abstracts
  An open, prospective study was undertaken to investigate the effects of enalapril on hemorheology in patients with renal disease and complicatinghypertension. Cellular and plasma determinants of blood viscosity and renal function were measured in 19 patients at baseline and 2, 60 and 120days...
Type: Abstracts

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