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Abnormal Rheologic Effects of Glyceryl Trinitrate in Patients With Non-Insulin-Dependent Diabetes Mellitus and Reversal by Antioxidants.
OBJECTIVE: To evaluate 1) the hemorrheologic and hemodynamic effects of glyceryl trinitrate in patients with non-insulin-dependent diabetes mellitus and 2) the influence of antioxidants on these effects. DESIGN: Case-control study. SETTING: University hospital clinic. PATIENTS: 40 patients with...
Tags: Nitroglycerin, Whole blood filterability (WBF), Whole blood viscosity (WBV), Platelet aggregation
Pre-treatment with allopurinol is able markedly to attenuate the deterioration in blood viscosity (BV) and whole blood filterability (WBF) that occurs after ischaemia during exercise. It also reduces the exercise-induced increase in serum oxidase activity, although this action is slightly less...
Effect of HMG-CoA Reductase Inhibitors on Red Blood Cell Membrane Lipids and Haemorheological Parameters, in Patients Affected by Familial Hypercholesterolemia.
Eighteen patients with familial hypercholesterolemia treated with lovastatin (40 mg/day) for three months were studied to find out whether the drug induces modifications in the lipid composition of the erythrocyte membrane and whether these induce changes in the rheological behaviour of the red...
Tags: Lovastatin, Whole blood filterability (WBF), Lipids, Erythrocyte aggregation (RBC aggregation), Erythrocyte deformability