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1. The shear stress of flowing blood profoundly influences the release of endothelium-dependent vasodilative and constrictive factors. Conversely, the influence of these mediators such as nitric oxide (NO) or endothelin-1 (ET-1) on blood rheology remains elusive. In the present study the...
Tags: Nitroglycerin, Whole blood viscosity (WBV), Shear rate, Shear stress (or wall shear stress WSS, endothelial shear stress ESS, vascular shear stress)
A study was carried out to investigate whether diltiazem influence blood rheology, as has been reported for some other calcium channel blockers. Twenty patients with clinical, stable angina pectoris were treated with 2 x 90 mg diltiazem per day for 2 weeks. Blood viscosity, plasma viscosity,...
Tags: Diltiazem, Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Red cell filterability, Peripheral vascular resistance
On the Effects of Dietary N-3 fatty Acids (Maxepa) on Plasma Lipids and Lipoproteins in Patients With Hyperlipidaemia.
An encapsulated preparation of fish oil (Maxepa) was administered to hyperlipidaemic patients in order to establish the responsiveness of thecommon lipid phenotypes to dietary supplementation with n-3 fatty acids. 13 patients took 6 g/day of fish oil and 12 patients took 16 g/day in arandomized,...
Tags: Omega-3-acid Ethyl Esters, Triglycerides, Low-density lipoprotein cholesterol (LDL-C), Very low-density lipoprotein cholesterol (VLDL-C), High-density lipoprotein cholesterol (HDL-C), Whole blood viscosity (WBV)
Changes in Blood Viscosity Following Nifedipine Administration and Its Relation to The Contents of Adenosine Triphosphate and 2,3-Diphosphoglyceric Acid in Red Blood Cells in Patients With Angina Pectoris.
The effect of oral administration of nifedipine (Adalat) on whole blood viscosity in patients with angina pectoris was investigated. Whole blood viscosityat a low shear rate of 37.5 s-1 was significantly reduced from 7.90 +/- 0.18 cP to 7.30 +/- 0.27 cP (1 cP = 1 mPa x s) after nifedipine...
Tags: Nifedipine, Whole blood viscosity (WBV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Shear rate
The purpose of this in vitro study was to assess the effect of 17beta-estradiol on hemorheologic parameters, namely on erythrocyte aggregation anddeformability and membrane fluidity. Blood samples from 65 women (aged 57 +/- 4 years) undergoing postmenopausal hormone replacement therapy were...
Tags: Estradiol, Whole blood viscosity (WBV), Plasma osmolality, Erythrocyte aggregation (RBC aggregation), Erythrocyte deformability