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The effects of statins have been investigated mostly in hyperlipidemic states so far. We analysed blood cholesterol, triglyceride, albumin, fibrinogenand gammaglobulin levels, haematocrite, hemoglobin, erythrocyte, leukocyte and platelet counts, blood and plasma viscosity and erythrocyte...
Tags: Atorvastatin, Erythrocyte deformability, Lipids, Whole blood viscosity (WBV), Plasma viscosity (PV)
As part of a randomized, single-blind, comparative study evaluating the efficacy of lovastatin and bezafibrate retard in the treatment of primaryhypercholesterolemia, hemorheologic parameters (whole blood viscosity, hematocrit, plasma viscosity, red blood cell aggregation and deformability, and...
Tags: Lovastatin, Plasma viscosity (PV), Whole blood viscosity (WBV), Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C), Erythrocyte aggregation (RBC aggregation), Erythrocyte deformability
Primary familial forms of chylomicronemia can lead to acute life-threatening complications, especially acute pancreatitis. The main aim of therapy is toavoid this so-called chylomicronemia syndrome. In 12 patients with primary chylomicronemia due to familial hypertriglyceridemia, the addition of...
Tags: Omega-3-acid Ethyl Esters, Chylomicrons, Triglycerides, Apolipoprotein B (ApoB), Total cholesterol, Very low-density lipoprotein cholesterol (VLDL-C), Plasma viscosity (PV), Whole blood viscosity (WBV), Erythrocyte aggregation (RBC aggregation)
The present study in female rats determined the effects of experimental hyperthyroidsm on hemorheological parameters and fibrinogen concentration. To induce experimental hyperthyroidism L-thyroxine (0.4 mg/100 g fodder) was added to the fodder of the experimental group rats for 20 d....
Tags: Levothyroxine, Whole blood viscosity (WBV), Plasma viscosity (PV), Fibrinogen, Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Erythrocyte deformability
The Hemorheological Effects of Raloxifene in Postmenopausal Women With Osteoporosis. Results of a 3-Year Placebo-Controlled Clinical Trial.
Raloxifene, the prototype of the selective estrogen receptor modulators, has been associated with an increased risk of venous thromboembolism. As hemorheological factors may be involved in thrombus formation this placebo-controlled study investigated whether raloxifene was associated with changes...
Tags: Raloxifene, Whole blood viscosity (WBV), Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Fibrinogen
Influence of Atorvastatin Versus Simvastatin on Fibrinogen and Other Hemorheological Parameters in Patients With Severe Hypercholesterolemia Treated With Regular Low-Density Lipoprotein Immunoadsorption Apheresis.
Low-density lipoprotein (LDL) apheresis is a treatment option in patients with coronary artery disease and elevated LDL cholesterol concentrations ifmaximal drug therapy fails to achieve adequate LDL cholesterol reduction. This therapy is more effective when combined with strong lipid-lowering...
Tags: Atorvastatin, High-density lipoprotein cholesterol (HDL-C), Low-density lipoprotein cholesterol (LDL-C), Plasma viscosity (PV), Whole blood viscosity (WBV), Red cell filterability, Fibrinogen, Erythrocyte aggregation (RBC aggregation)
The effects of acute morphine administration on intact erythrocytes and on their flow properties were studied by measuring the mean cell volume, cell geometry, and whole blood and plasma viscosities. Morphine caused a small (2-7%) increase in mean cell volume. Changes in cell geometry were found...
Tags: Morphine, Mean corpuscular volume (MCV) (or mean cell volume, mean erythrocyte volume), Plasma viscosity (PV), Whole blood viscosity (WBV)
Relationship Between Plasma Essential Fatty Acids and Smoking, Serum Lipids, Blood Pressure and Haemostatic and Rheological Factors.
We aimed to determine whether levels of plasma fatty acids are correlated with other potential risk factors for cardiovascular disease, using a sampleof patients from a cross-sectional survey of the general population, in the City of Edinburgh. 306 men and women aged 55-74 years of whom half...
Tags: Omega-3-acid Ethyl Esters, Plasma viscosity (PV), Whole blood viscosity (WBV), Lipids, Triglycerides, Fibrinogen, High-density lipoprotein cholesterol (HDL-C)
Haemorheological Effects of Losartan and Enalapril in Patients With Renal Parenchymal Disease and Hypertension.
The objective of this study was to compare the effects of the angiotensin II (ang II) antagonist, losartan and the angiotensin-converting enzyme inhibitor (ACEI), enalapril on haemorheology. Twenty-nine patients with renal parenchymal disease and hypertension were enrolled in the prospective,...
Tags: Enalapril, Losartan, Whole blood viscosity (WBV), Plasma viscosity (PV), Fibrinogen, Erythrocyte deformability
Modification of Transoperative Changes in Blood Fluidity by Hydroxychloroquine: A Possible Explanation for the Drug's Antithrombotic Effect.
A study was carried out in 40 patients undergoing minor surgery to investigate the effect of hydroxychloroquine on haemorrheological parameterswhich might explain its reported anti-thrombotic action. Twenty patients received 600 mg to 1400 mg hydroxychloroquine sulphate in the 48-hour period...