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Relationship Between Plasma Essential Fatty Acids and Smoking, Serum Lipids, Blood Pressure and Haemostatic and Rheological Factors.
We aimed to determine whether levels of plasma fatty acids are correlated with other potential risk factors for cardiovascular disease, using a sampleof patients from a cross-sectional survey of the general population, in the City of Edinburgh. 306 men and women aged 55-74 years of whom half...
Tags: Omega-3-acid Ethyl Esters, Plasma viscosity (PV), Whole blood viscosity (WBV), Lipids, Triglycerides, Fibrinogen, High-density lipoprotein cholesterol (HDL-C)
Haemorheological Effects of Losartan and Enalapril in Patients With Renal Parenchymal Disease and Hypertension.
The objective of this study was to compare the effects of the angiotensin II (ang II) antagonist, losartan and the angiotensin-converting enzyme inhibitor (ACEI), enalapril on haemorheology. Twenty-nine patients with renal parenchymal disease and hypertension were enrolled in the prospective,...
Tags: Enalapril, Losartan, Whole blood viscosity (WBV), Plasma viscosity (PV), Fibrinogen, Erythrocyte deformability
Modification of Transoperative Changes in Blood Fluidity by Hydroxychloroquine: A Possible Explanation for the Drug's Antithrombotic Effect.
A study was carried out in 40 patients undergoing minor surgery to investigate the effect of hydroxychloroquine on haemorrheological parameterswhich might explain its reported anti-thrombotic action. Twenty patients received 600 mg to 1400 mg hydroxychloroquine sulphate in the 48-hour period...
Atorvastatin Improves Blood Rheology in Patients With Familial Hypercholesterolemia (FH) on Long-Term LDL Apheresis Treatment.
To determine the effect of atorvastatin on blood rheology in patients with familial hypercholesterolemia (FH) on regular LDL apheresis, weprospectively studied the rheological variables fibrinogen, plasma viscosity, red cell aggregation, whole blood viscosity, hematocrit and plateletaggregation...
Tags: Atorvastatin, Erythrocyte aggregation (RBC aggregation), Whole blood viscosity (WBV), Fibrinogen, Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF)
The effects of acute morphine administration on intact erythrocytes and on their flow properties were studied by measuring the mean cell volume, cell geometry, and whole blood and plasma viscosities. Morphine caused a small (2-7%) increase in mean cell volume. Changes in cell geometry were found...
Tags: Morphine, Mean corpuscular volume (MCV) (or mean cell volume, mean erythrocyte volume), Plasma viscosity (PV), Whole blood viscosity (WBV)
Effects of Long-Acting Propranolol and Verapamil on Blood Pressure, Platelet Function, Metabolic and Rheological Properties in Hypertension.
The newly developed antihypertensive drugs, the long-acting beta-blocker propranolol and the sustained release calcium antagonist verapamil, arecompared in their antihypertensive, platelet function, rheological properties and metabolic effects. The trial was a double-blind, randomised, placebo-...
Tags: Verapamil, Propranolol, Plasma viscosity (PV), Whole blood viscosity (WBV), Fibrinogen, Erythrocyte deformability, Low-density lipoprotein cholesterol (LDL-C), High-density lipoprotein cholesterol (HDL-C), Platelets (or thrombocytes), Lipids, Platelet activation, Platelet aggregation
Effects of Low-Dose EPA-E on Glycemic Control, Lipid Profile, Lipoprotein(a), Platelet Aggregation, Viscosity, and Platelet and Vessel Wall Interaction in NIDDM.
OBJECTIVE: To assess the effects of low-dose eicosapentaenoic acid-ethyl-ester on diabetes regulation, lipid metabolism, blood rheology, andplatelet reactivity. RESEARCH DESIGN AND METHODS: In a double-blind, randomized, placebo-controlled study, 24 NIDDM subjects received 1800 mg of EPA-E, 900...
Tags: Omega-3-acid Ethyl Esters, Plasma viscosity (PV), Whole blood viscosity (WBV), Platelet activation, Platelet aggregation, Low-density lipoprotein cholesterol (LDL-C), Apolipoprotein B (ApoB), Erythrocyte deformability
A Human Model of Platelet-Leucocyte Adhesive Interactions During Controlled Ischaemia in Patients With Peripheral Vascular Disease.
AIMS: In humans, little is known about the effects of platelet-leucocyte interactions on blood viscosity and microvascular perfusion. This study testedthe hypotheses that (1) activation and interactions between platelets and leucocytes may have an impact on microvascular blood viscosity...
Tags: Clopidogrel, Whole blood viscosity (WBV), Platelet aggregation, Platelets (or thrombocytes), Shear rate, White blood cells (WBC) (or leukocytes)
High-Dose Atorvastatin Treatment in Patients With Peripheral Arterial Disease: Effects on Platelet Aggregation, Blood Rheology and Plasma Homocysteine.
BACKGROUND: Statins are used for the treatment of hypercholesterolemia. Although they are well known to have pleiotropic effects, their dose-dependent influence on platelet aggregation, hemorheologic properties and the plasma levels of homocysteine in patients with peripheral arterial disease (...
Tags: Atorvastatin, Erythrocyte aggregation (RBC aggregation), Whole blood viscosity (WBV), Plasma viscosity (PV), Hematocrit (Hct) (or packed cell volume PCV, erythrocyte volume fraction EVF), Platelets (or thrombocytes), Platelet aggregation
Lovastatin Therapy in Hypercholesterolemia: Effect on Fibrinogen, Hemorrheologic Parameters, Platelet Activity, and Red Blood Cell Morphology.
The effect of lovastatin therapy on blood rheology was investigated in 26 hypercholesterolemic patients. Treatment with lovastatin was associated with a significant improvement in whole blood filtration time and a tendency toward normalization in red blood cell morphology. A significant increase...
Tags: Lovastatin, Fibrinogen, Platelet aggregation, Platelets (or thrombocytes), Whole blood viscosity (WBV), Plasma viscosity (PV)